Epidural clonidine used as an adjunct to local anesthetics has three distinct mechanisms of action. To start with, the stimulation of alpha-2-receptors in the dorsal horn decreases pain transmission. Next, clonidine could cause local vasoconstriction that restrictions vascular elimination of regional epidural anesthetics. Jun ten, 2024 · If clonidine https://bradl268tqk8.wikicorrespondent.com/user