Abstract The present study focused on the role of microRNA-139-5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS). Applying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) within the rat anorectrum. we identified miRNA-139-5p as differentially expressed RNA repressor with highest expression in the purely phasic sm... https://www.chiggate.com/