Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central nervous system, conolidine modulates alternate molecular targets. A Science Innovations review located that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By influencing https://travisvygum.blogkoo.com/considerations-to-know-about-alternative-natural-pain-relief-to-replace-traditional-painkillers-57158244