Investigate into conolidine has brought about discovery of an opioid receptor in the body known as ACKR3/CXCR7. ACKR3 is apparently one of the most popular focus on for conolidine, which also disregards another four classical opioid receptors(three). There exists desire in applying conolidine like a pain-reliever according to proof https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers